FOLFIRINOX - new prognosis by reducing?

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Hello. New to this support. My father has terminal pancreatic cancer and has had three rounds of chemo. The first two rounds were just the 1st and 3rd chemical of the cocktail FOLFIRINOX and after his third, he has suffered really badly with stomach issues and hair loss, so the oncologist has decided to reduce his treatment back down to just the 1st and 3rd chemical - missing out the really strong 'IRI'. He didn't ask the oncologist what the new prognosis was with this reduced level of chemo and so I was hoping this community might be able to shed some light so that we can better prepare ourselves as a family. Thank you.

  • Hi  and a very warm welcome to the online community which I hope you'll find is both an informative and supportive place to be.

    I'm not a member of this forum but noticed that your post hadn't had any replies. Responding to you will 'bump' it back to the top of the discussion list.

    While you're waiting for replies, it would be great if you could put something about your father's diagnosis and treatment to date into your profile as it really helps others when replying to you and also when looking for someone on a similar pathway. It also means that you don't have to keep repeating yourself. To do this click on your username and then select 'Profile'. You can amend it at any time and if you're not sure what to write you can take a look at mine by clicking on my username.

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  • Hi Speak to the Clinical  Nurse Sprcialist attsched to his Consultant. They will bd able to advise and spport 

  • Hello, its difficult to answer a very specific question in relation to his chemo regime..but, the way to view it I think is, some is better than none! All of the drugs will impact his health and yes the strong, most potent one you mention is being missed out, so that will help with how he tolerates it. Could it not be reduced, rather than skipped completely, or is that just not feasible? it differs very much with person to person.

    My Dad, when he was having Folfirinox following surgery, found a reduction was easier to tolerate and his platelet count wasn't so drastically affected.

    When he had a different type of chemo further down the road, he managed this much better- they were Abraxane and Gem...I forget the long name! A much gentler type of chemo regime, but usually used for a more palliative approach.

    What have the nurses said about it, or the Oncologist?