Oliparab

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I've been taking oliparab for a while and am struggling with nausea and vomiting a lot.

My consultant has reduced my dose from 600mg to 400mg because of this but I'm now concerned that they won't be so effective at lower dose. Has anyone else had their dose reduced?

  • Hello there - so sorry to hear you're getting nausea & vomiting - I too am on Oliparib and my dose has been reduced to 500mg a day (250 taken at am & 250 taken at pm) as it was really lowering my immune system ( & I'm still on targeted chemotherapy). Ironically having gone through full chemo for stage 4 ovarian, the only time I've considered sickness tablets is with taking the Oliparib! I've since found I get no nausea when I've eaten something - in the morning all I need is a small spoonful of yogurt (for example) then take my morning dose, and for me it really works. By the evening I've usually eaten dinner and have not had nausea then. Even when I don't always feel like eating in the morning the yogurt has always helped me. My thinking is that even on a slightly lower dose my body will respond better, as I understand it, it builds up in the body too? x