Niraparib causing emotional problems

No experience of niraparib but was on olaparib for a few years and remember to feeling very "off" for weeks at the beginning. I did not like how I was feeling but decided to give it 2 months to see if things improved. They did improve. Not entirely but enough to enable me to keep taking it.

Hi there

I don't have experience of Niraparib as yet but I also have stage 4 ovarian cancer, mine is a rare type called CLEAR CELL & I have been advised this is the drug my Oncologist wants me to take as maintenance treatment as Avastin (the recommended drug for clear cell) is causing so many side effects. 

I wonder how I will react to this too? 

What have your team advised? Do the symptoms calm down do you know? Xx

So far, they haven't advised anything apart from stop it and see.... But then, the cancer will come back quicker, so I really don't know what to do. I'm seeing the consultant in a couple of days so we'll see what they say. They don't seem very well informed on Niraparib generally, perhaps because it's a fairly new drug? One of the questions I will be asking is whether the symptoms will reduce with time. 

I've stopped the Niraparib at the moment and do feel better without it. I'm really disappointed, I so wanted to be okay with it x

Hi

i have been taking niraparib since July 2023. I was initially taking two tablets 200 mg and was ok with them for a couple of months . But the. I got terrible constipation and felt really unwell and my blood count went down. The nurse took me off the tablets for 2/3 weeks. I the saw my consultant again and she reduced the dose to 100mg a day. I have been fine since , occasional bouts of constipation but nothing major. Don’t know how much you are taking but it might be worth checking to see if it could be reduced.