After a reduction in dose of Dab and Tram, and 3 stops and restarts after infections, my partner's cancer team feel he may have too much sensitivity to Dab and Tram, and want to discuss changing treatment to another targeted therapy, encorafenib and binimetinib.
Has anyone else made the same change? Just wondered what the side effects are, and hoping he can tolerate them better than Dab and Tram. He has just gone to A&E again.
Thanks
Margyy
Hello Margyy, sorry to hear about your hubby being in A&E.
I am currently on encorafenib and binimetinib since mid November. I didn’t swop onto it but I did have the single drug dab back in 2015.
I don’t know if you’ve looked up the side effects, I’ve put a link below, I think they are listed as similar to dab tram but when I started my oncologist said they tend to be well tolerated by most people.
I seem to be one of those people who tolerate what ever drug they throw at me quite well. I was being sick before I started the drugs but was put on anti sickness meds that worked and I continued on them just in case for the first few weeks but I’m not taking them any more. My skin is very dry and I’m using e45, nothing else really to report.
I am a type 2 diabetic and need to eat at regular times as I’m diet controlled, these meds suit me much better as although you have to stick to the 12 hour times, you are allowed to eat and drink with them so it’s much more relaxed. There are more tablets though, I take 3 in the morning and 9 at night and 6 of them are quite big, capsule shape but bigger than your average paracetamol. It took me 45 mins the first few days to get them all swallowed, and the amount of water taken can be a problem for waking up during the night to go to the loo at times. In hind sight I might have done the tablets the other way round. I did it this way as I thought I might get less side effects if I’m in bed or asleep for the majority of tablets, one common was was drowsiness.
I hope the swop is good for him and if you have any questions come back to me.
Hi KT
Thanks for your reply and information.
I thought you had mentioned previously that you were taking these, but I see many others who have had these 2 treatments.
We are hoping that the side effects won't affect him so much, so he can get some quality of life back.He is so worried that he will be running out of treatment options.
Hopefully he will be out of hospital tomorrow, and can concentrate on recovering first.
Will see what his cancer team say next week.
Margyy
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