I posted this elsewhere and was asked to share it here. In January 2017 my husband, then 83, was diagnosed with stage 4 metastatic melanoma. There was a mass under his left arm, and there were small lesions in both lobes of the liver, both lungs and in the bone of the sternum. I took him to a specialist in Florida and she gave him 4 infusions of Opdivo and Yervoy through March and April. Scans in September 2017, March and September 2018 showed him to be absolutely clear, not a trace of it. He will have another scan next month. Only 10% of patients apparently, have any side effects from these drugs and he had none, luckily, except a slight drop in one of the blood cell counts which righted itself quickly. I think it may have accelerated his dementia a tiny bit but one doesn't know for sure. A fringe benefit was the disappearance of many of his basal and squamous cell skin cancers but some did come back.
But those drugs clearly work.
