Pembrolizumob

Hello I’m on Pembrolizamab for stage 3d melanoma. All good until 6 out of 9 treatments. I didn’t really have an option not to take this opportunity for Pembro. All people are react differently. I hard decision for you to make.

Thank.you

Hello

i I had nine pembro treatments for stage 3b melanoma finishing in July 2025. I’ve had joint pain since the second treatment. I assumed it would clear up after I finished treatment but it’s got worse. I go onto methotrexate next month.

Wishing I hadn’t had immunotherapy. Feel like I wasn’t advised well of the risks. My oncologist told me the joint pain was ‘categorically’ nothing to do with the Pembro but linked to an old neck injury. I knew that was rubbish but what can you say? My second oncologist accepted it was but was very slow to refer me to rheumatology. I’m suffering really badly and very angry I’ve been lumbered with what seems likely to be a permanent problem. Sorry that’s not very encouraging for you. 

Hi   thanks    I  am  already on  methotrexate and  the  ongolist know this      think  he was  humming and aching about this  was a  telephone conversation    they now  called me in to have a  chat      on  Tuesday   we will  see  what  happens 

Best of luck for Tuesday. The rheumatologist told me they just don’t really know about long term impacts of immunotherapy because it’s a relatively new treatment. But she did say I was the fifth person she’d seen just that week who had immunotherapy-related joint pain. I’m part of a medical study which aims to predict better who gets what side effects from the treatment which will hopefully help future patients. 

Well  done to  you.   I  will  let  you  know what happens 

Many  thanks for  replying back to my post