Nivolumab/Relatlimab treatment for Stage3c Melanoma

Your medical team are best placed to advise re liver impacts and you really should ask for guidance without embarrassment.

As a mother who could have lost a child to a rare liver reaction with medication that had similar advice to yours (the actual medication was immunosuppressant rather than booster but very similar guidance on alcohol, I believe), am horribly aware both that reactions can be highly individual but also liver load matters and you are adding to your liver stress.

To sum up, I think it is the case that alcohol raises the risk of an interaction and it sounds to me as if you may be over-doing it especially (possibly even regardless of – I am not familiar with your exact medication) whether you take other medications/supplements.

Fatigue can actually be a sign that the liver is under stress. 

In a nutshell, no one on here will be exactly similar to you because they don't have full picture regarding your medications, liver status etc. But as a mother who has been through the horror of bad liver numbers with a much younger relative who was drinking well within guidelines yet whose liver numbers ended up matching those of a severe alcoholic (took many months to recover and can never have that medication again now), I feel passionately you should speak to your team about this rather than carry on blindly.

Rose x