Mom's memory decline after diagnosed with Mantle Cell Lymphoma

FormerMember
FormerMember
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What can I do to investigate why my mother has experienced progressive memory loss? MCL is in remission after treatment with Rituxin. But, her short term memory loss is getting worse. She has had Mini MMRI test for Alzheimers and passed with almost perfect score. She has high Eocynophils each time we have a check up. Any tests or recommendations would be appreciated.

  • Hi  and welcome to the Online Community, although I am sorry to see you finding us and so sorry to hear about your mum.

    Good that your mum has achieved remission but as always, the post treatment journey throws up curved balls.

    The positive is her mini MMRI scan for Alzheimer’s was good but I have no idea about Eocynophils. 

    How long since she had her last treatment?

    How old is she?

    We also have our ‘Ask an Expert’. section where you can post questions to our mostly Volunteer Experts but please allow 2 working days to get a reply.

    You can see my story by hitting my forum name, but my journey was rather long and complicated but it did take me years to over come the effects of some of my treatments........ and yes this did include short term memory loss.

    Keep posting as it does help.

    Mike (Thehighlander)

    It always seems impossible until its done - Nelson Mandela

    Community Champion Badge

  • Hi again, just had a look at Eosinophils.

    What are her team saying about these cells?...... as they are described as “active participants in many immune responses. However, eosinophils can also be damaging as part of the inflammatory process of allergic disease”

    You need to talk with the experts to get their take on this.

    Mike (Thehighlander)

    It always seems impossible until its done - Nelson Mandela

    Community Champion Badge

  • FormerMember
    FormerMember in reply to Thehighlander

    Thank you for your timely reply.  She is 74 years old and has been in remission for 5 months.  Our concern seems her memory is getting worse instead of better. 

    We have an appointment with the oncologist today. Before she has her next maintenance treatment of Rituxan,  I want to make sure that she is not experiencing a side effect of the medication. 

    Thank you for the  information on Eosinophils.  I will ask the doctor about it.

  • FormerMember
    FormerMember

    Dear tmesp

    Go to Google Scholar and check out chemobrain or cognitive impairment .

    Also if she had BR (bendamustine with rituxan), is is known to cause cognitive impairment.

  • FormerMember
    FormerMember in reply to FormerMember

    She did have Bensamustine. Thank you so much. This is the first time I have had anyone acknowledge what I have suspected all along!

  • FormerMember
    FormerMember in reply to Thehighlander

    Doctor said she must have had some sort of infection, (sinus) or some underlying problem that caused the rise  . Eosinophils.  They are back down to a normal level. Thank goodness. If we could just get her memory to improve,  life would be much better for her.

    Thank you for your help.

  • Hi chemo brain can be something that stays with us post treatment, some days you don't notice and other days you learn to go with the flow and acceptance of that can make like much easier especially for the patient. 

    we all know this is a roller coaster ride, where we ride blind, never knowing where the highs and lows are
  • FormerMember
    FormerMember in reply to FormerMember

    Hello

    I sent you a friendship request so we can talk off line.

    Yours

  • FormerMember
    FormerMember in reply to FormerMember

    Thank you. I have accepted it!