Flying after 3.5 months surgery

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I had lower lobectomy last June and I’m on Osimertinib tablet for just over a month now. I feel fine aside from few mild side effects of the tablet. My breathing is fine, I still feel tightness and numbness post surgery and sometimes nerve pain on the area. I have a Mexican cruise coming in a week time which means flying to LA from Heathrow- a 12 hour flight. The surgeon/ oncologist said that I’m fit to fly and that I’ll be fine. Is there anyone in here who has done and no problem flying a long haul flight after 3 months of the operation. Thank you in advance.