Cabometyx woes

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Hello, I’m sorry that we are exclusive members of a club none of us wanted to join. My husband started Cabometyx 3 months ago (adjuvant Keytruda didn’t work). The side effects have been unmanageable, 2 “vacations”, dosage lowered to 40. He’s currently unable to walk without pain, just worried he’ll be pulled off altogether. Aside from the usual topicals, (urea, steroid) elevating and cooling, any other strategies we haven’t discovered yet?