Vaccine Trial update

Thank you Trish. He was on immunotherapy nivolumab, but the tumour still progressed. The consultant did say that sometimes the immunotherapy can change the dynamics and make it more receptive to chemo. I’m hoping this is what’s happening but until he has a scan we can’t be sure. Like you my husband is happy to try anything which gives him hope. He’s not giving up yet! I will discuss these options with his consultant. 

Awww, Tilly Mint 61,  I am sorry to hear the b*****r is now resisting the treatment.  When I went on the trial, my nivolumab had already got good results so I was a bit indifferent about the trial, thinking "it won't work because the nivo is doing its stuff".  I'm not sure the rationale for my thinking really!  But then a member on the kidney or incurable group shared this post and your results and it was so motivating.  I changed my expectations from "zero" to wanting the same response I had had previously with nivo (5.9cm > 2.6cm).  "I'll be at NED in no time" I thought.    You've got to dream, think big. LOL   My feet are back on the ground now and onwards we go.  

I hope you get on the fortify trial.   Good luck and best wishes xx

Hi Trish,

great and encouraging news  

good to read about it, and thanks for sharing it…

Love from marta x

Hello,

my husband has had 7 rounds on nivolumab and ipi…… the cancer has shrunk a lot.  Did your husbands cancer shrink and then progress or did it just not work ? Just wondering how it might  progress for us……

My husband only had nivolumab which didn’t work. He had 5 treatments, one every 4 weeks. This was following 3 chemo, and 30 chemoradiation. None of them made any difference. 

Oh so sorry to hear this. Everyone is different, I know things can change for us at any time. It’s hard ….

Thank you. He’s on a different palliative chemo now, but we are hoping he can be put forward for a trial. He wants to keep trying anything available and ge has a great positive mental attitude. 

We are very positive too , chemo did make my husband poorly and the cancer grew back shockingly quick after chemo stopped but the immuno seems to be working ….

We pray it continues to work for him x

Thanks Hazel, it is disappointing but I suppose that's the chance you take when you sign up. Hoping the next one is 'the one' .... currently enjoying the break between them. Apparently the next one is quite heavy going 3 times per week but no pain no gain.

Hope you are keeping well.

• I'll update you when I know more xxx