Hi, was wondering if anyone has been offered to take part in the JADE trial? It’s being offered to my partner who has cancer of the tonsil and neck. She’s 1 week post 2 chemo and 30 radiotherapy sessions and they are looking to speak to us in the next week. I’ve done loads of research and they have given us a fairly well informed pack. Would be good to connect with anyone who is currently in the trial or in fact been involved in the first two phases. She’s 47 still working and the commitment is significant so trying to establish as much as we can before taking any decisions.
thanks Gillian
Hi Gillian. I did a quick search for you and there aren’t any posts in this group. Somebody who is part of this trial but who doesn’t post may see your post and join in.
Meanwhile I can say that I have a friend who is now four years clear of T4 throat cancer treated with the usual CRT plus another checkpoint inhibitor Durvalumab.
Durvalumab and Dostarlimab are both checkpoint inhibitors but act in different ways
Dostarlimab targets the PD-1 receptor, while Durvalumab targets the PD-L1 protein…. but I’m sure you probably know this.
Dani
Base of tongue cancer. T2N0M0 6 weeks Radiotherapy finished January 2019
PS. Checkpoints are being investigated in the curative setting so your partner is at the sharp end of this. Plain CRT has always been the standard but anything that increases the chance of cure must be really welcome.
I wish you all the best and do please update us if you decide to go ahead and do actually get selected for the drug.
Dani
Base of tongue cancer. T2N0M0 6 weeks Radiotherapy finished January 2019
What TNM is she?
Dani
Base of tongue cancer. T2N0M0 6 weeks Radiotherapy finished January 2019
She sounds in good hands. Look after yourself too and stay with us Hugs xxx
Dani
Base of tongue cancer. T2N0M0 6 weeks Radiotherapy finished January 2019
