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Can someone explain to me why an unknown primary in the oropharynx (hpv) does not relate to an unknown primary cancer anywhere else in the body?  Someone mentioned it in this group but I was never told the reason why it’s not as “serious as other cups. God bless

  • Can someone explain to me why an unknown primary in the oropharynx (hpv) does not relate to an unknown primary cancer anywhere else in the body?

    Do you mean two separate unknown primary cancers? 

    Dani 

    Base of tongue cancer. T2N0M0 6 weeks Radiotherapy finished January 2019

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  • No.  His dx is hpv oropharynx of unknown primary.  He has no spread.  Was diagnosed as a stage 1

  • Sorry I still don’t understand what you mean. 

    Dani 

    Base of tongue cancer. T2N0M0 6 weeks Radiotherapy finished January 2019

    I BLOGGED MY TREATMENT 

    Macmillan Support Line -  0808 808 00 00 7 days a week between 8am-8pm

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  • The biopsy of the lymph node would show squamous cell carcinoma. SCC is a cancer of epithelial cells so it can arise only in those cells. So that’s the cells lining the mouth and throat, larynx, the tubes in the lungs, the oesophsgus,  the cervix and the skin.  

    Dani 

    Base of tongue cancer. T2N0M0 6 weeks Radiotherapy finished January 2019

    I BLOGGED MY TREATMENT 

    Macmillan Support Line -  0808 808 00 00 7 days a week between 8am-8pm

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  • I was worried about my husbands unknown primary but someone had said unknown primary of head and neck hpv is not treated in the same way as a different unknown primary ex:  lungs, colon. 
    in other words it’s not as serious possibly. Drs aren’t that concerned because the primary wd most likely be in the area of the oropharynx. I’m sorry I cannot explain this any better. Maybe someone will know what I mean. 

  • Or do you mean could the cancer found in the lymph node have come from anywhere else apart from the oropharynx? 

    Dani 

    Base of tongue cancer. T2N0M0 6 weeks Radiotherapy finished January 2019

    I BLOGGED MY TREATMENT 

    Macmillan Support Line -  0808 808 00 00 7 days a week between 8am-8pm

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  • I guess I’m wondering that yes

  • All lymph nodes drain particular areas of the body. The neck nodes drain parts of the head and those areas are largely specific. A lymph node under your ear won’t drain your eye for example. So the likelihood that this cancer has arisen in the oropharynx is high, very high. Why would an SCC arising in the oesophagus, say, manifest in a neck node unless there was evidence of cancer elsewhere? 

    Dani 

    Base of tongue cancer. T2N0M0 6 weeks Radiotherapy finished January 2019

    I BLOGGED MY TREATMENT 

    Macmillan Support Line -  0808 808 00 00 7 days a week between 8am-8pm

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  • Sorry I don’t know what you mean. Are you saying the likelihood that it spread to a diff area is very hogh?  He has scc hpv oropharynx hpv 16 pos stage 1 of unknown primary.  

  • . Are you saying the likelihood that it spread to a diff area is very hogh

    No. Exactly the opposite 

    I’m saying that the chances the primary is in the oropharynx is high. Isn’t that what you’ve been told already by the doctors? 
    Perhaps you should tackle your husbands oncologist and voice your worries. 

    Dani 

    Base of tongue cancer. T2N0M0 6 weeks Radiotherapy finished January 2019

    I BLOGGED MY TREATMENT 

    Macmillan Support Line -  0808 808 00 00 7 days a week between 8am-8pm

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