Onset of severe symptoms - any warning signs?

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I have OC that is inoperable and have had radical chemoradiotherapy that failed. (Partial response). As yet no signs or symptoms of locally advanced or metastatic disease but I know it is only a matter of time. 

I am relatively asymptomatic at present just night time acid reflux that is controllable.

I would like to go on holiday to Europe as a solo traveller for 5-7 days before I am unfit to do so but I am worried that severe symptoms of OC may come on all of a sudden whilst I am away.

I am interested to hear from those who have experienced the onset of severe symptoms such as inability to swallow or anything related to metastatic disease. Did this happen suddenly or were there any warning signs?

Thank you.