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At last, 8 months after diagnosis, my husband's FOLFOX chemo has started - two rounds so far. Unfortunately, the weeks before treatment started, he started suffering from the most dreadful diarrhea. Loperamide seemed to keep it relatively under control but after round 2 of chemo, it's come back with a vengeance. We'll be contacting the specialist nurses tomorrow as we want to avoid another hospital stay to rebalance the electrolytes: anyone else had the same? Any idea how long it might last or what else we can do other than pump litres of fluid through the PEG and titrate the loperamide up? Thanks

  • Hi  

    I'm sorry you have not had a reply to your post. I have had a different type of cancer so I hope you don't mind me replying. By responding it will place your post back at the top where it may be seen by more members of the oesophageal group.

    I hope by now that you both have seen the specialist nurses and have had some help and advice. If you still need some support, consider ringing the Macmillan helpline, this is the link to contact


    I hope you get more replies and personal experiences. Best wishes for your husband's treatment.

    A x

    What is a Community Champion?

    I am a Macmillan volunteer. 

    Macmillan Support Helpline

    0808 808 00 00 

    7 days a week between 8am -8pm

  • Thanks so much for your reply and your concern - the nurses agreed we should administer OTC rehydration salts and titrating the loperamide up has stayed the attacks. We think they'll prescribe something stronger when we see the oncologist next week. 

    One of the curious aspects of caring for someone with cancer is that it seems in some cases that the side effects are both more demoralising as well as life-threatening than the tumour itself. Just an observation,

    Thanks again.

  • I had severe diarrhoea from my chemo, loperamide didn’t help that much , but I was prescribed codeine phosphate tablets ( the codeine comes in different strengths) which really helped. 

  • Thanks - we did hope the morphine might work but if no joy, we'll hit the codeine. Kind of you to reply.