Rituximab Query

Hi Daniel646ba9 as part of my treatment for my 2 rare T-Cell NHLs I had about 600hrs of Ritriximab (over 6 cycles) as part of my R-EPOCH between late 2013 to April 2015 and honestly I had no issues and it did the job….. although I did go on to have Stem Cell Transplants and am 19 years out from my second SCT.

Lets see if anyone has had Ritriximab on its own. 

Hi Mike,  thank you for sharing , much appreciated and good to know you had no issues with it. 

Hi Daniel I had 4 treatments of Retuximab 8 years ago to treat stage 4 low grade FL. I had a reaction at first but they slowed down the drip and all was fine. I am still in clinical remission which is great. Hope this helps.

Jo

Hi Jo good to hear from you.

Your reply reminds me that although I had no real issues with all the drugs I had over the years including Rituximab…… I often need to remember myself that I have a life long ‘significant’ allergy to lots of drugs….. so all the way through my many treatments I was on significant IV antihistamines and the drug infusion rates were always much slower than normal…… but I had great sleeps during my treatments ;)

The bizarre, even miraculous thing is now that I am post Allograft SCT my clinical team are confident that my drug allergies are now gone due to the fact that my big brother had no allergies and as he was my Stem Cell donor my immune system/bone marrow have taken on his immunity!!!!!

….. and 10 years on I have had no drug reactions. 

Hi Jo, 

That is fantastic, so 8 years of remission from induction rutuximab only ?

This fills me with hope 

Thank you 

Hi!

I was stage 4 FL and had rituximab and bendamustine, very slowly with lots of anitihistimine because of my Ritux allergy.   I'm currently back on it again as a component of R-CHOP because my remission faltered after 6 years.  Oddly, I now get rituximab via a subcutaneous injection into my belly.  This sounds horrrible, but it's okay if you pinch hard while the drug goes in.  It's really quick, saves me hours in Chemo and there's no sign  of an allergic reaction at all.

The rest of my -CHOP is quick to give, so I'm only on the unit for a couple of hours max.  But I must ask why my Ritux allrgy seems fo have disappeared... umless anyone here knows?

Cecren

Hi Cecren,  thank you for sharing,  I am glad you managed to get a 6 year remission and I hope you able to achieve another long remission with your current regime.

All the best