Ribociclib fulvestrant and denosumab

Hi Hennie

i take Palbociclib so same group of drugs.

i started on ribociclib which took my white blood cell count very low and I ended up in hospital for a week with sepsis in the first month.  Since then the white blood count has been carefully monitored and my drugs altered to a lesser dose and now it’s more stable. As for hair, I’m 54, my hair feels thinner whereas it’s been much thicker, I put this down to my age as well as the drugs, small price to pay if the drugs keep me alive 

happy to connect xx

Thanks for the reply Bassy1969.  Hope you are doing ok. I too think it’s a small price to pay for keeping me alive. I  was really just wondering if it was common side effect on this kind of combination of drugs xx

Hi, I'm on Ribociclib & letrozole as 1st line treatment. I'm just starting cycle 7 & still on full 600mg dosage ! My hair thinned quite a lot & isn't really growing as it did before, although the last few weeks I think it's starting to grow back now. I've managed to avoid infection & neutrophils & wbc are just starting to become a near normal range !! I hope you manage well as at my 1st scan results showed really good shrinkage. 

Hi Hennie. I'm on ribociclib and letrozole since diagnosed with bone mets in May 2023. I've had 3 hospital admissions with cellulitis, one unknown infection and now with recurrent kidney infection and stones. Although not directly related to the cancer, because of my low neucount I was at risk of sepsis. My dose is now reduced to 400mg.

Its been a roller coaster and I've missed a wedding and 2 holidays.  It's made me feel very unsure about booking anything! My hair has definitely thinned a lot.

However, I'm written to you waiting in in the airport after a lovely week's holiday. I hope things remain stable for you..

Best wishes.

Sea Ranger. 

I'm on Ribociclib and letrozole. 

My hair is very thin now and I have bald areas.

Due to the Ribociclib.