Hi Hat
I am sorry you are facing treatment decisions. My cancer isn’t oestrogen driven and in some ways I was glad not to have to make a decision about letrozole. From what I have seen on this site, some people have very few side effects whilst other people find it very difficult. All treatments have risks and benefits and I guess you have to look at it in the context of your health, any other medical conditions you may have, and how you like to spend your time. The option of trying it to see how it affects you is always there.

Macmillan Support Line - 0808 808 00 00, 7 days a week between 8am-8pm
I am a Macmillan volunteer.
I have metastatic Triple Negative Breast Cancer, in remission
Whatever cancer throws your way, we’re right there with you.
We’re here to provide physical, financial and emotional support.
© Macmillan Cancer Support 2026 © Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). Also operating in Northern Ireland. A company limited by guarantee, registered in England and Wales company number 2400969. Isle of Man company number 4694F. Registered office: 3rd Floor, Bronze Building, The Forge, 105 Sumner Street, London, SE1 9HZ. VAT no: 668265007