I changed to Exemestane after just over 3 miserable months on Anastrozole.
Exemestane, certainally over the first 3 months was much more tolerable. However I am now just over 5 months into treatment and I am finding the tiredness, stiffness and joint pain is increasing. Am I correct in my thinking that after 6 months, the side effects become gradually easier ?? I am hopeful that I am almost past the worst of the side effects 
Also, I have the beginning of a trigger finger in my right hand and a trigger thumb in my left hand. The symptoms ease with use but I only need to rest for a short period for them to stiffen and stick again (evenings and overnight are the most difficult). My GP has offered to inject them, but if Exemestane is the cause, will the problem just come back or affect other fingers ??
Hi Susz
It’s really sad that you are at the point of stopping your 2nd AI. How long have you been taking the Exemestane for ?
I am keeping everything crossed that after 6 months I will get used to the medication and my symptoms will ease .
The first 3 months I took Exemestane the side effects weren’t too bad, but since then they have gradually increased. But not as severe as I experienced with Anastrozole.
My BC nurse has said that if I don’t want to take the Exemestane, they will prescribe Tamoxifen for me to try (even though at 64, I am way past the menapause).
