Kadcyla for HER2 positive BC

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Hello lovely community

Ive finished chemotherapy (Docetaxel and carboplatin)and I’ve just had my lumpectomy and lymph node biopsy results showing that I still have some cancer cells in both still.

I’m now having to change from 3weekly injections of Phesgo(immunotherapy) to 3weekly infusions of Kadcyla.

Does anyone have any experience of Kadcyla? I asked the Dr if I needed any more chemo and he said no but my research showed that it’s immunotherapy and chemo combined!
Does anyone know if it’s definitely infusions? ( really don’t want another PICC line)

And are the side affects as bad as with Docetaxel?

I have an oncology appointment in two weeks but wanted some clarity before then.
many thanks for your time

ral 24 days ago

Hi pottyaboutclay

I had chemotherapy lumpectomy and radiotherapy. I was also put on kadcyla for 14 rounds . Yes it is an infusion and you also have to have bloods a couple of days before each infusion. I know everyone is different and I also suffered really badly with Docetaxel but kadcyla was a breeze, apart from feeling tired for a couple of hours after the infusion had no other side effects and also managed to work through the treatment.

If you have any specific questions please feel free to ask.

Carolyn x

Las60 23 days ago

I had a very similar treatment plan, and like yourself felt very dubious about changing from phesgo to Kadcyla. I have to say it really wasn’t as bad as anticipated, apart from horrendous mouth ulcers which cleared up after a dose reduction.
In an odd way it felt like a soft landing after finishing chemo, as I still had lots of contact with the oncology team.

I had my picc line removed as they said it was unnecessary and used a cannula for each infusion.

Good luck , it’s very ‘doable’

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