Exemestene weight gain

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I was on Letrozole for 8 months and then had significant depression so my oncologist stopped hormone therapy.  I restarted hormone therapy after a 8 months  gap switching to Exemestane 25mg.  I have been on this for 5 months and my weight is piling on even though I exercise .   I am just reaching out to see if the weight increase has happened to anyone else and how you managed.   

  • Hi. I was on Letrozole and immediately piled up about 2 stone in a month. I was eventually changed to exemestane. I didn't lose any weight but it stabilised. I can't recommend anything because I am now 4 years on and will shortly be coming off aromatase inhibitors, and I will see then if I lose weight.  My osteoarthritis has worsened and inhibited my exercise, although I do an hour of aqua exercise 5 days a week. Sorry I can't be more positive, but I do wish you luck. When I come off my meds in the summer, I will do a few posts to let people know how soon and if normality returned. xxx

  • Hi Susie

    I am on Exemastane but only been on it for three months.  I have put weight on but then I have been comfort eating and although I try and eat healthy food in the day, I have been eating cakes and biscuits and chocolate after my evening meal so that doesnt help.  I am going to try and be more healthy because my cancer is hormone receptive and carrying extra weight doesnt help.    I think I need some inspiration.

    Lee x

  • Thank you so much for your kind reply.   I am sorry about your weight increase but well done for persevering.  I wish you all the best and hope things improve for you once  you finish  hormone therapy medication.

  • Hi Lee.  Thank you for your kind reply.  Since I have been on Exemestane I have also been binge eating and its mostly sweet food.   I think Exemestane must have affected my metabolism and given me increased appetite.  I am constantly hungry and more so in the evenings.  You are not alone and you dont know this but you are already an inspiration to many because you have faught this awful disease and its not easy at all.  Keep going and inspiring others including me.  You are amazing.  

  • Wow thank you Susie70 that is so kind of you.  Unfortunately there are a lot of people in my situation with secondary cancer .  There are some really awe inspiring people that keep me going too.  We are all in this fight together.  Hope you are doing as well and you an be and here if you want to chat.

    Lee x