Letrozole v quality of life

Hello Cloudier,  here are a couple of links. One is super detailed but a good slow read.  I saw it on YouTube when I searched for emerging treatments for ER.+ breast cancer.  Take care too.

https://www.hematologyandoncology.net/archives/august-2021/new-targets-in-endocrine-resistant-hormone-receptor-positive-breast-cancer/

https://www.uh.edu/news-events/stories/2022-news-articles/february-2022/02212022-trivedi-breast-cancer-biomarker-drug-target.php

These researchers are amazing and our best hope in finding out a way to prevent breast cancer not just treat it.  Maybe some day..

Barbara

Thanks for posting about the fasting, hadn't read that.  Like you I am trying to reduce my risk of recurrence, taking Letrozole, plan to start the diet soon, no alcohol, daily exercise and reducing red and processed meats, increasing fruit and veg.  I never knew that like smoking, alcohol and red/processed meats are class 1 carcinogenic.

Thank you for posting so quickly. 

Absolutely.  If you go on YouTube and search Dr Li you will be glad you did.  He is fabulous and has worked on the development of many cancer drugs too .  I have his book Eat to beat disease and it is wonderful.  I even gave a copy to my breast surgeon when he retired.  
Eating close to the earth is the most healthy.  I try to eat mostly organic too especially the dirty dozen.  Another good book is the China Study but very big book to read.  Can watch about it on YouTube.  Someone else I like to watch on YouTube is Dr Kristi Funk MD a breast surgeon from Beverly Hills California.  She is excellent too and her book is good.   It is called Breasts the owner’s manual.  
Well that is enough of my favorites.  Would love to hear who you all like too.  
Barbara

Thanks Barbara, I will do, may even buy that cookery book too x  

Hi RemyD - thanks for your reply  and for mentioning the NHS Predict breast cancer tool. This has been very useful for helping my partner decide on which treatments to follow. It was a little surprising that this online tool was not mentioned by any of my partner's breast cancer unit team, considering that it was developed by NHS oncology experts and is freely available to use online. https://breast.predict.nhs.uk/

Thank you to everybody who has taken the time to reply to my original post. All your comments and suggestions have been very useful and are helping my partner make the right decisions for her on the treatment path ahaed. We both really appreciate your thoughtfulness and kindness. Thank you all.

Hi Tom Thumb, I’m so glad that the forum has been helpful. Like your partner, no-one mentioned the ‘Predict Tool’ to me. I think this might be because a year or so ago, it was considered by many to be out of date, but in a good way. When I last looked (about a year ago) it did not include radiotherapy, for example. At that time, it was undergoing a review, as the data was based on the longitudinal statistics for patients treated many years before, and treatments have since improved. There was no consideration of how receptive the tumour was to hormones either - for me the figure was high, and that’s why I was advised to not stop taking my medication. Hope that helps further. 

I was surprised that I didn't know about this tool from the NHS.  I believe it helped me to make an informed decision in my particular case.  Good luck to you partner whichever decision they make.

This is from the Predict website on future versions:

We hope to introduce the effect of tumour progesterone receptor expression (PR status) on outcomes, and the benefit of radiotherapy. In the longer term we also hope to be able to display data on the recurrence of disease, showing women how long they might be able to expect without their cancer coming back.

We also plan to extend the site so as to be able to display a quantification of the potential harms of treatments (i.e. the proportion of similar women expected to suffer each potential side effect or adverse event). This will enable the potential harms to be considered alongside the potential benefits of each treatment.