This is my cocktail of drugs, due to start next month. 3 sessions each of EC and Docetaxel, then a year of Herceptin injections, plus radiotherapy. Does anyone know why these two different drugs are used? Why not EC all the way through? It is a question I am going to ask at my next appointment but just wondered if anyone had asked it before. I can see that for my type of cancer (HER2+ ER-) Herceptin is good at targeting this so understand that but I am concerned about Docetaxel as some of the side effects look horrible and I don't want to be left with more problems after treatment. I was Stage 1 Grade 3, they got everything out and there was no spread so very lucky I know.
The different drugs attack the cancer cells in a different way. There will have been lots of research trials to show which drugs work best. My combination was EC-P, but my tumour was ER positive HER2 negative. Paclitaxel and docetaxel are in the same class of chemo drugs - I don't know why some use one rather than the other.
Hi Ginny
bio is on profile if you want to read
my original plan was EC x3 then docetaxel x3 followed with Herceptin x 18 also bisphosphonate infusions x 6over three year hopefully last treatment in June .
Docetaxel was removed from plan on first appointment with onco ,this was because of my previous bowel problems which had led to resection .
So I was put on EC x 6 .
Both EC and Docetaxel affect different people in different ways .I have read on here of people who felt better on Docetaxel than on EC and vice a versa .
Personally I managed on 3 EC far better than some then cumulative Side effects kicked in for last 3 .I was offered a change at no 4 but I stuck with it .
I don’t know the medical reasons for the mixes but everyone one reacts differently and so can their cancer so have a discussion with onco so you can both be happy with plan
Whatever cancer throws your way, we’re right there with you.
We’re here to provide physical, financial and emotional support.
© Macmillan Cancer Support 2025 © Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). Also operating in Northern Ireland. A company limited by guarantee, registered in England and Wales company number 2400969. Isle of Man company number 4694F. Registered office: 3rd Floor, Bronze Building, The Forge, 105 Sumner Street, London, SE1 9HZ. VAT no: 668265007