Grade 2 ER+ HER-2- breast cancer with 1 lymph node positive - chemo?

Thanks for good wishes . My first chemotherapy was fine , sickness is very well controlled now and just 3 days of fatigue. My second one was hard i don't think I drank enough water and I got a blood clot. My  clot seems to  have gone now I have to inject myself every night. It's made me very anxious but I'm going to have the next one , next week.  As it's just a precautionary chemotherapy then only need 4 cycle's. I will make sure I drink lots next time and hopefully it will be better. Take care 

Jayne X 

That's good that you reduced your reoccurance score with Chemotherapy by such a lot. You are very brave deciding to have chemotherapy. I'm so thankful that we have access to these treatments even if they are a little difficult on times X 

Thank you to you all for sharing your stories and thoughts through this difficult phase. It was helped me so much and, although I don’t know you, I think about you a great deal The results from my Prosigna Test showed I was very low risk of reoccurrence and my oncologist did not hesitate in reassuring me that chemotherapy would not be of benefit so I am having radiotherapy and hormone therapy. I wish you all the very best and hope for all of us that this was just a ‘blip’ in our lives. Take care. X

That’s great news. So glad for you. I was the same and had 5 sessions of radiotherapy and hormone tablets. 
you will soon be out the other side… then treat yourself. You deserve it

hi Dahlia, I have the same type of cancer but had two tumours.  I also had mastectomy and 17 nodes removed, and only one positive, which showed macro metastasis.  I am advised not to go for Oncotype as with large positive lymph node, I should have better survival rate with Chemotherapy.  I am 49 and overall in good health.  I would much rather have Chemotherapy knowing that I did what I can to reduce the chance of reoccurrence.  Do you know what drugs and number of cycles  they will use for Chemotherapy?

I have the same presentation as you . It's 4 cycle's of EC chemo best wishes x

Thanks, all the best to you too x

Hi, I’ve been following this thread not realising I was about to have the same question.  I have had bilateral invasive ductal breast cancer (Er+/HER-) however the 2nd was found a month after I’d completed treatment for the 1st.  I have very dense breast tissue.  This 2nd one has been tricky, Mammogram missed it, Ultrasound classed it as indeterminate probably benign, initial HER2 was borderline but after further tests negative and then when there was no sign of lymph node involvement the pathology results confirmed one was actually positive.  Basics I just don’t trust it if that makes sense.  The 1st one  was full of the normal worry but lumpectomy, RT, no lymph node involvement and hormone blockers it was fairly straight forward.

Oncotype isn’t available to me as this 2nd find has essentially been pre-treated with the Anastrozole for 4 months and further more pathology shows the cancer hasn’t reacted to the medication at all.  

So my logic is if my cancer is not as estrogen receptive as first thought then I’ve lost the benefits from the medication per the nHS predict tool therefore  the extra benefits of chemo is more important - whatever the %.  Not sure what 2nd Gen/3rd Gen means but without medication the benefits are 1%,2%&4% for 5/10&15 years (2nd Gen) and 2%,5%&7% (3rdGen).   I know my oncologist will go through it all with me and they will have (and understand) all the other info from MDT, pathology etc but just wondering what your thoughts are ?? to help me with my questions for the oncologist.

I’m pretty calm about it all at the moment (a couple of wobbles) but it is still all consuming in my thoughts.  

Hi Moco, I had a bilateral mastectomy as I had two tumors one in each breast. Its difficult to find out you have two cancers. For most people the worry that they will get another cancer in the other breast can be very difficult. But for us we are at that stage already, nevermind,  you have had some treatment and the cancer has not reacted to the medication , I think that the option may well be to have surgery and some preventive chemotherapy, this seems to be the standard for most people on here . The surgery will remove the lump and any lymph nodes , if affected and the chemotherapy should stop it returning. It might be that surgery is enough, but just prepare yourself that a little more chemotherapy may be needed . For most, preventive chemotherapy is 4 sessions of EC . But wait and see you have been through so much and just a little more path to travel before you are back to normal x Take care 

Thank you Rhiwbina, I have had the lumpectomy and node removed. The positive lymph node was a shock.   I think I just expected the treatment plan to be the same as the other side - chemo wasn’t in my radar at all. The consultant has said to give chemo some thought and referred me for an appointment to chat the pros/cons through with the chemo oncologist but I think my mind has settled on this being the next step.  Whatever it takes I think.  It will be after Xmas so just going to try and enjoy the next few weeks.  I have researched everything throughout but not chemo so that is very helpful to know about the EC type. Is that once a month?  I hope you are getting through your treatment well xxx