Optima prosigna genetic trial- unsure

Hi there HopefulForChristmas.

I don't think that your Drs would recommend chemo if it was not necessary. Where I am, it would not be one Dr who would make the decision, but the full MDT [muliti disciplinary care team]. Decisions are usually made based on a risk-benefit analysis. If there is any doubt at all, ask for an explanation of the risk-benefits of going ahead with chemo, versus the risk-benefit of not getting the chemo.

I dont know your age, but you could also ask the oncologist what treatment they would want for their wife/daughter/sister/mum, if they had the same as you, knowing what they know about the diagnosis and the treatment options.

Wishing you good luck and the very best of treatments.

Wallydug

Thank you WallyDug. I’m 40. The oncologist at my first appointment started with saying I should have chemo then suddenly switched to tell me about the trial as he can sometimes be surprised. I’ve since had a second oncologist appointment with the trial dr and she’s obviously very much for it and sounded sensible. I have another appointment on Monday with a completely different oncologist so totally confused about what is right for me. I just want it gone and over with, giving me the best chance of being there for my children.

I believe that in trials some people get the new drug/regimen versus some people who dont and they compare the results for the new treatment to the -non new. I think the people who do not get randomised to the new treatment get the treatment which is already approved by the NHS and is the best available to date, for whatever is the patient's situation. 

Ask about risk-benefits for you from whatever they are suggesting. It is important to understand what is to happen to you and to be happy with your decision.

Wishing you all the best.

Wallydug

Thank you x