Does anyone know if having a higher hormone receptor reading makes it more aggressive ? It was something a consultant said that made me think it is. Mine is ER 8. PR 8.
Snap! I was told that the scale of 1-8 is level of responsiveness to hormone treatment with 8 being most receptive. I hope this helps and I'm sure a fuller response will follow from other forum users
I have never been told it's to do with aggressiveness. My understanding is same as Bongo, it's about how responsive to hormone the cancer is/was. So if you are +8 you are a good candidate for hormone therapy.
Yes, I know the higher number means the cancer is more receptive to these hormones. But does it make them harder to treat. ? Does it make it more aggressive? It's just that I saw a private consultant last week who said I should have an MRI due to the fact my cancer was highly hormone receptive and family history. .....it left me thinking.
ER+/PR+: About 65% of estrogen-receptor-positive breast cancers are also progesterone-receptor-positive. This means that the cells have receptors for both hormones, which could be supporting the growth of the breast cancer.
Regarding the presence of these receptors "supporting the growth of the breast cancer". ER-positive breast cancers have the most favorable outlook of all molecular sub types.
Any positive test result — whether just for estrogen receptors, just for progesterone receptors, or both — means that the breast cancer is considered “hormone-receptor-positive.” Hormonal therapy may help to slow or stop the growth of hormone-receptor-positive breast cancers by lowering your body’s estrogen levels or blocking the effects of estrogen. These medications also may reduce the risk that the cancer will come back (recur).
I was at the oncologist yesterday as I didn't want to take any AI like anastrazol she explained the numbers.On a scale of 1-8 is the amount of aggressiveness of the hormone receptors not the cancer itself, so as I am 8 she said I was the highest risk of these cells producing oestrogen which the cancer can feed off and therefore put you at more risk of an earlier recurrence.
In fact it was the amount of detail she gave that actually made me change my mind and take the hormonal therapy treatment.
Dreamthief is the person for this sort of thing as he is a marvel with the stats. I don't know how to tag but hopefully someone else can.
My cancer nurse told.me.it was excellent news because of being pot menopause as this means not producing much of either anymore and because receptive to hormone treatment at a high level would.make it far more easy to treat. If you are pre menopause then you are producing more but again hormone treatment should be highly effective you just have a different type maybe tamoxifen for pre menopause.
