Abmecicleb

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Has anyone been reduced from 100mg to 50mg? been on this tablet for  nine months picking up 10 cycle tomorrow . Just wondering if 50mg still a help 

  • Hi. I’m on my 7th cycle of abemiciclib and this is my second cycle at 50mg. My oncologist agreed this was for the best as I felt so poorly and my wbc kept dropping too low and I would have to stop taking the tablet.

    im going to have another chat with my oncologist as I still feel poorly and very fatigued even on this low dose. I think my oncologist seems to think that any amount of the drug is good. 
    I call it the evil drug - I know it is a fantastic drug and I am privileged to get it but it’s going to be a long 2 years!! 

  • Cycle 14 for me, I agree 2 years is a slog!

    Best wishes x 

  • Hi 

    I’m on cycle 8 , it’s hard going imo ! My onco said 50mg is still effective if taken properly as advised , it has to be better than nothing surely ? 
    Im still on 100mg , the fatigue really gets me down sometimes 

    Have your side effects been tough ? Xx

  • I am constantly tired, have watery eyes, lack of appetite plus I have to take anti sickness tablet every day and several times a week I have to take loperamide.

    im on tamoxifen too so not sure which is the culprit!!!

    it’s all good fun!!! Everyone thinks you should be fine now that the main treatment has finished but I feel pretty rubbish! 
    how have you been on the tablet?

  • I agree , everyone thinks you’re ok , it’s so frustrating . Grateful to have access to these drugs of course but it’s hard going 

    My gastric issues have improved since my dose has been reduced but definitely still there and the fatigue , some days it’s hard . I’m on Prostap & letrozole too , joys haha 

    Oh also , my BCN and onco both said 90% of patients they look after are on antidepressants! I’ve had to have mine increased recently 

    xx

  • I can definitely understand why people would feel depressed. I think I’ve coped pretty well during the horror of my cancer diagnosis. Have not really felt depressed but, I am having some anxiety. Mostly regarding driving and being out and about. I’m stuck at home a lot as I’ve not returned to work yet. I am feeling a little bit down due to the fatigue I’m feeling - really don’t feel like doing much as I feel so tired.