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I had / have suspected painful bladder syndrome and I take d-mannose. It is good for UTIs, but also I have found it has calmed my bladder down. Do you also do bladder training? Holding off going o the loo for longer and longer periods of time? That is very useful too.

I actually found that going into menopause has really helped me - I was pre-menopausal and now on zoladx and exemestane. For some reason, that has calmed everything down for me.

I also use regelle moisturiser twice a week - definitely helps calm everything down in that area nd has made a significant difference to atrophy - which was pretty bad after chemo. 

Hiya,

thanks for your reply. I have never heard of d-mannose  but have just googled it. Do you know which is a good brand and do you take as powder or capsules?  I will definitely try this. 
yes I have seen a physio and had bladder training and do pelvic floors every day now. 
i use Ovestin (estriol) cream twice a week for the atrophy which works.
 I’ve come to the conclusion that the solifenacin and Mirabegron although helping a little are not sorting this problem and perhaps I have been mis diagnosed as the original diagnoses was over the phone during covid as an over active bladder. 
i will contact my doctor and discuss possibility of having bladder pain syndrome (interstitial cystitis). 
Your reply has been very helpful thank you so much. I get so down sometimes as having bladder pain and such issues makes it hard to deal with every day life as I’m sure you can imagine yourself.