Update

Not surprised you can't sleep, it's a lot to process.  I'm guessing Friday can't come quick enough fir you to find out how they going to treat xxx

Yes, it's a nightmare diagnosis. Irish, I have a few questions, not sure how much you are willing to share so I am going to ask, just ignore anything you don't want to answer.

What type of breast cancer is it and what treatments have you been given so far? How did they confirm the tumour on the liver, did they do a biopsy? What made them scan in January 2021 to look at the spine?

I will be thinking about you tomorrow, and I hope you post again soon, and after the consultation.

Sorry to hear this Irish, I hope you’re getting lots of love and support at home and on here I know you’ll get some great advice and support too.  Be thinking of you Friday xx

Carcinoma left breast, grade II (T3P3M1) duct NST, pT2 (40mm), pN1a (3/8 lymph nodes positive), MX, ER 8, PgR 8, Her2 1+, all margins 4mm or more. Breast Surgery Lymph Node removal Radiotherapy as chemo wouldn't have helped and on Letrozole. Scans every 3 months so 3 MRIs CT/Bone Scan/Body Scan. MET to L5 Spine found Jan 2021 inoperable so had SABR (Stereotactic ablative radiotherapy) £24,000 a Treatment to try to halt it. Scans Sep were ok have some Lung Nodules but small. Jan Scans picked up Liver Lesion had additional MRI on Liver and then PET CT For Liver so confirmed. So review with seems to be one of UK Top Liver guys tomorrow so will have to wait and see. I also have the PIC3CA Mutation so have been holding off going on CDK4/6 Inhibitors but will have no choice now as Letrozole not working so thats my story!

Thanks all for support

Thanks, Irish. The SABR procedure should have "frozen" the spine tumour; was it successful in doing that? It's an excellent alternative to surgery and I am glad they did that. (I was refused this procedure for what at the time were thought of as mets on my lungs, ironically because they were supposedly mets. I guess hospitals' criteria vary from one to the other.)

That gene alteration is a b!tch, I am glad they are monitoring you closely. From my own end, I have a gene alteration too but a different one. Seeing Genetics in a few weeks and I intend to ask about being tested for the one you mentioned as well as three others that flagged to me of interest. This is not just for myself, but for my children and the extended family.

Back to the liver, I'd be interested in what their plan of attack is. It seems more and more that nowadays they are aiming, with greater and greater success, to turn certain types of metastatic cancer into "chornic disease" rather than what they used to be. The CDK4/6 is probably not a bad example of that. I am now hoping that this new approach will do the job for everyone where the Letrozole had failed.