Has anyone given up on letrozole and started another drug. I Carnt stand the side effects any longer. I changed to femera two months ago after six months on another brand Is anyone able to take these tablets and lead a normal life xx. I’m going to make an appointment to see my consultant see if he will change for me x
HI Figgy2019
I'm not on Letrozole (Anastrozole for me). But have you researched coatings on all the brands for Letrozole? I did this research on Anastrozole and Teva and Accord had similar coatings and then another one that I had been given had significantly different ingredients in its coatings. I had been given this one when they didn't have any Accord - and OMG the side effects!!! I had barely anything on Accord but this one, it was like I had been run over by a truck, I ached so much. I then asked for Teva when they ran out of Accord again - and was fine,
Other than this, by replying to your post, there may be some ladies around now who see your post as I've bumped it back to first page.
Best Wishes, Lesley
Hi, I've been on Letrozole for 6 months and not experiencing any side effects other than being a bit stiff in the mornings. Hope this helps
Hi Figgy2019
I’ve been on Letrozole five months, suffered with insomnia and hand pains three weeks into my first box, consultant allowed a six week break but insomnia continued but it’s not as bad now. Since the aim of these AI’s is to remove oestrogen from our body, it follows that certain effects are due to this depletion. My symptoms have settled somewhat which is apparently usual after six months. I’ve had Manx, Accord and the Sun Pharma brands, not by choice but were supplied by my pharmacy over the months. Femera is the original brand Letrozole, the others are all generics. Like Lesley, I also researched the brands and their ingredients. I informed my pharmacist not to give me the Teva or Cipla brands. Cipla has tartrazine as an ingredient, don’t understand why they felt the need to include this as tartrazine is a known bad reactor.
Hope you find a solution. Best wishes x
Eline
Thankyou for your reply. Which brand are you on please. I am taking femera I was on crescent before. I think I might give it another six weeks see how I go x
Hi, femera is the original Letrozole, the others are generics, so the same drug, but in different packaging (the only way I can describe it). I have heard many people tolerate femera best. Best wishes to you.
Whatever cancer throws your way, we’re right there with you.
We’re here to provide physical, financial and emotional support.
© Macmillan Cancer Support 2025 © Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). Also operating in Northern Ireland. A company limited by guarantee, registered in England and Wales company number 2400969. Isle of Man company number 4694F. Registered office: 3rd Floor, Bronze Building, The Forge, 105 Sumner Street, London, SE1 9HZ. VAT no: 668265007