Letrozole/Anastrozole side effects

FormerMember
FormerMember
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Hi,

I have been taking Letrozole for 4 months now and really suffered from joint pain, I spoke to my BC nurse and she suggested I have a 4 week break and then start taking Anastrozole to see if that is any better for me.

I just feel really miserable with this pain, I'm so stiff when I get up in the morning and after I've been sitting down. It's mostly in my knees but recently I've started getting pain in my hands and fingers too. I've already had surgery for carpel tunnel a few years ago but it feels like the same pain as that and I know it can return even after surgery.

I'm just reaching out to see if anyone has the same issues and what they do to relieve the pain, also if anyone has switched from Letrozole to Anastrozole. I know its different for everyone but don't know where else to turn to.

  • Hi Kay56

    I have been on letrozole for about 7 months now and like u have suffer with bad joint pain. I am so stiff when I get up and struggle to get up after sitting, I look hunched and bent !

    I do find the more active I am the better it all is and am determined to take it as I know how effective it is.

    Xxx

  • Hiya,

    I had a mastectomy 7/4 and have been on letrozole from 2 weeks before my operation. 

    My ankles and feet stiffen up after sitting for long periods and when I get up in the morning find it hard to walk for a couple of minutes but then ok.

    I have started the couch to 5k 3 weeks ago and also go for long walks and I honestly think this is helping.

    Probably worth a try. Staying positive too helps enormously.

    Hope this is helpful.

    Regards

    BoobyJ

  • FormerMember
    FormerMember in reply to Booby J

    Hi, thank you for your replies, I do find that keeping active helps, just been out for quite a long walk now, it certainly doesn't make things any worse.

    I find the mornings are worse but once I get going it does improve things. I've always been an active person and never suffered with joint aches and pains so I think it has come as quite a shock to be dealing with this. Having said that, I do consider myself lucky that my breast cancer was in the early stages so very treatable. Staying positive about that does help too.

  • Hi,

    I've been taking letrozole for 5 months now and on my (3rd) current brand have significantly less side effects, like you mine was mainly knee centred and made getting my lazy ar5e off the sofa that much more challenging (& grunty!) and walking up the stairs was a real joy.  On first brand I was also really stiff on a morning.

    Might be worth switching brand as there's a few ladies on here that have similar experiences?

    Worth noting that my recent change of brand coincided with first bisphosphonate infusion which may also have helped or may be causing recent improvement in aches & pains?

    Hope that your pains get better.

    Sam

    My secret? Being daft & staying positive.