Colon Cancer

Hi Sopranina

I've just been asking about how to take the Metoclopramide. Will be interested to hear  how you work out the best 

time to take them.  Yes I think the tiredness is worse straight after your infusion. Wishing you all the best too.

Trish xxx

Thank you Kath, that is a big help. 

Actually I've just seen that my tablets are Domperidone and I should take 1 tablet 3 times a day.  Maybe your tablets were different and you were able to take 1 per day.  Many thanks. I am very grateful.

Trishxxx

Hi Sopranina

Not really got any tips on the nausea but as Katz51 says would take the anti sickness tablets just to prevent it. Jay just felt nauseous for a little while and then for some reason it left him I don't know if it was maybe he eat something that didn't agree with him or with the meds he's on. He does from time to time suffer from heartburn and said this at one of his appointments and they prescribed omeprazole for that it's a tablet you can have when and if you need it just I think like an indegestion remedy. Jay likes drinking a lot of milk too and he finds if he has bad heartburn he will drink a glass of milk and this seems to lift it too. 

Vicky x

Hi Trish,

Sorry to hear about your experience. I had the same operation and 21 nodes removed. All nodes were clear except they found an extramural venus invasion and some cancer cells in a deposit outside the colon wall. Staging T3N0 but extra risks meant stage 3 diagnosis and 4 3-week cycles of CAPOX. I'm now on day 18 of the first cycle.

With the Oxaliplatin infusion I had some stinging in arm towards end of the 2-hour infusion. On recommendation I had put a folded T-shirt over my forearm to keep it warm. The nurses can provide heat pads during infusion and I'll ask for one on cycle 2. Immediately after the infusion I had pains along the vein up to the elbow and down to the wrist. I had quite bad peripheral neuropathy immediately and couldn't anything cold. Even fresh clothes from a drawer cause sensations like frostbite in my fingers. This symptom eased after 2 days from about 7 out of 10 on my pain scale (10 being almost unbearable) to about 4 out of 10 on day 3. It gradually eased off until iI barely noticed it by day 15. There are many different options to deal with it and your doctor can prescribe other drugs to counter the effect. Personally I'll be asking for something to take the edge off it for next cycle.

I wish you best of luck with the rest of your treatment.

Kind regards and blessins,

Alan

Hi Alan, thank you for your reply.  I have just had my 4th infusion of Oxy on Monday and am now on 2 weeks of Capecitabine.  My worry is if peripheral neuropathy goes to my feet and remains after chemo has ended which could affect my quality of life. I have tingling and pins and needles in my hands and the odd shooting nerve pain in my left foot today.  If it starts getting worse in my feet I will stop Oxy and ask to just take the Capecitabine.  These next few weeks will determine if I carry on with Oxy.  (I still have 4 more cycles to go).  

I wish you all the best with your cycles/treatment and thank you for replying.  It is much appreciated. 

Best wishes.  Trish

I realised after my reply that your message was a few months old. Sorry about that. Our circumstances might be slightly different, but the oncology doctor treating me is involved in research and she has me on 4 by 3-week cycles of CAPOX. I'm taking 4 CAP tablets twice per day for 14 days after the 2-hour Oxaliplatin infusion on day 1. Her treatment is based on fairly recent research that showed 4 cycles was as effective as 8 cycles bar a fraction of one percent. With 4 cycles it gives a 20% improvement of 5-year survival rate. Her analysis was that doing 8 cycles just increases the impact of side effects without any significant improvement on outcome. It may be worth asking your doctor what are the implications of stopping after 4 cycles and/or getting a second opinion.