Mum diagnosed with Bile Duct Cancer

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My mum has recently been diagnosed with inoperable bile duct cancer. Feels totally fine in and of herself. Starts chemo on Friday which they have told us is classed as palliative because the surgery to remove tumour is too risky so it has been deemed inoperable. A really confusing journey between her late Oct diagnoses and now as all the biopsy come back negative but other scans confirm suspicion of cancer. Anyone else had experience of bile duct cancer where biopsy wouldn’t confirm - it’s given us all false hope up until now