Acute myeloid leukemia, IDH1 and ivosidenib/tibsovo

  • 0 replies
  • 20 subscribers
  • 35 views

My wife was diagnosed with AML and a mutated IDH1 gene (December, 2023). Treated with azacitidine and Venetoclax starting January 2024, which helped for 18 months, then she relapsed. Her condition worsened really bad, but after couple of months was  prescribed Tibsovo (2x250mg), which works great for now. My questions to the forum if anyone has the same condition and treatment: how long have you used this drug with or w/o side effects, and if you had to reduce the dose due to side effects did it still work? Our oncologist says she may develop resistance to the drug eventually. Thank you.