Hello all
For all you wonderful people who have followed my threads over almost 3 years and given invaluable advice, I just want to let you know my wife was re born yesturday with her Sisters cells. Now day +1 and doing well. Started today on ciclosporin to suppress her immune system. We are well aware of the long long road ahead but following her conditioning and transplant, she is feeling OK with nausea and diahorhea her only issues.
She was given an anti sickness injection day before transplant and had severe hives immediately, unbelievably after one Piriton tablet they completely disappeared within 1 hour, very odd.
Expecting her levels to drop rapidly in next 2 days so will be aware of things that may/are likely to occur.
We are currently staying in the hotel for Ambulatory care patients just round the corner from the macmillan Cancer Centre at UCLH. we are however expecting my wife to be transferred into the main Hospital unit within the next 2/3 days as infection risks increase. That's when I will have to leave her and head home. TBH I will feel much more comfortable in the knowledge she is in the main unit with help at hand immediately should she need it and,she feels the same.
So far, so good, praying all continues well.
Fulhamboy (Nick)
Hi Nick, a great update and you do know that she will now be looking for two birthday’s every year including two gifts.
Infections are unfortunately normal post SCT but it took a good year for me to have my first one - this is how different each journey can be.
Its been a long journey for you both so let’s look for a lid to be put in this and you can both move on with life.
The preference is for her levels to be left to climb by themselves. For both my Allo’s my Cyclosporin levels were not reviewed until about day +100.
Yes the donor cells need to populate her bonemarrow then after about 100 days the real battle starts.
Yes I was on the drip in the unit then onto oral meds…… they are rather disgusting so be prepared for this to be a challenge.
They will do the first of a number of Chimerism genetic blood tests about day 100 and most likely a BMB. These are used to monitor the success of SCT by evaluating the ratio of donor and recipient DNA in her blood looking for the donor cells to be higher than her cells.
They will also start look to start reducing the anti-rejection drugs and let her old self fight with her all new self fight for her immune system looking for the Donour to win. At this point in time she will be open to GvHD as her old self will try to kill off her new cells.
