Turning that elusive corner

FormerMember
FormerMember
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This was triggered by the cig03  response to my versed tribute to my friend's special relationship with his ever supportive wife - see my contribution to "a poem by JamesValvis".

I read the profile of cig03 and can appreciate her anxiety about the unfolding drama that is her misfortune to face. So please don't lose heart my friend because the pace of change in recent times is something to behold. I provide an example of one such source of optimism. There are others - it is just a question of how many corners we need to negotiate before we reach another goal.

The illustrious T – Cell a pointer to the future of cancer treatment

Although discovered over half a century ago it is only in recent years that what is often termed “specialised helper to B cells” known as T cells have assumed greater prominence in the battle to find successful ways to overcome the menace of cancer.

The foundations of cancer treatment were previously surgery, chemotherapy and radiation therapy; augmented by targeted drugs. The approval by the US Food and Drug Administration in 2017 allowed T cell therapy to be used on B-cell lymphoma patients who had relapsed after at least two kinds of other treatments.

Since that time treatment opportunities have widened and there are several UK centres able to provide T cell therapy for lymphoma and leukaemia. It involves taking white blood cells (T cells) from the patient and reprogramming them so that they able to target cancer cells.

The future

Up to now T cell therapy has been aimed at blood cancers, but there are those confident enough to predict that solid tumours could also be subjected to this type of treatment; indeed, a BBC report in January of this year reported on a discovery by scientists at Cardiff University that identified a part of our immune system that could successfully treat prostate, breast, lung and other cancers  according to lab tests.

The Cardiff team discovered a T-cell and its associated receptor that could find and kill a wide range of cancerous cells in the lab including lung, skin, blood, colon, breast, bone, prostate, ovarian, kidney and cervical cancer cells.

Crucially, normal tissues were untouched.

Perhaps we shall learn more about the progress of this potential breakthrough in due course. I will  certainly try to keep abreast of developments.

  • Hi

    I'm just 'tagging' so that she will see this response to her post in another thread.

    It's great that you've taken the time to post this as it offers hope for anyone with cancer.

    Take care x

    Community Champion Badge

     "Never regret a day in your life, good days give you happiness, bad days give you experience"

  • FormerMember
    FormerMember in reply to latchbrook

    Thank you for that kind message. I am grateful you took the time to tag cig03.

  • No problem Slight smile

    Community Champion Badge

     "Never regret a day in your life, good days give you happiness, bad days give you experience"

  • Thank you very much, Discourse. I certainly like to believe something will come along...

    CLG03...
  • Hi, Discourse,

    I was tested for a trial before they decided to operate (about this time last year). I think it was for this type of therapy, but I didn't qualify. My blood didn't have whatever they needed to give me this therapy. Also, by January, when I might have joined a trial, all trials had been closed due to COVID. Phewee... But should my star not stay as shiny as it currently is, I do hope I will have bought some time and something else might come along.

    Thanks for sharing. I didn't see that at the time. I was swimming through dark waters...

    Hope you're keeping well, if it's not a strange thing to say.

    CLG03...