Hello great hive mind!
Do any of you have any experience of taking Aspirin with Tamoxifen? My type of breast lump is HER2- ER&PR+ with ostensibly no spread so, at the moment, no chemo, just pre-surgery Tamoxifen lasting for at least 5 years, surgery & reconstruction in a few weeks, then radiotherapy (so long as they don't find anything more suspicious in the mastectomy material). I've also developed high cholesterol from sitting around eating cheese for a year, and may have been experiencing some effects from that in recent months.
I put myself on high dose Aspirin for a short time to help unclog my system, whilst also reducing the cholesterol I was eating in my diet. I am now reducing the dose to the old recommended 75mg a day to ward off future stroke/heart problems. However, my GP says that the use of Aspirin before having any significant symptoms of heart attack or stroke is now out of date and the risks of gastric bleeding from Aspiring outweigh its benefits.
I've read a couple of articles about Aspirin working with Tamoxifen to increase Tamoxifen's effect, and the use of Aspirin to disrupt cancer stem cells both to prevent cancer recurrence and to treat triple negative breast cancers where chemo has little effect. I've also read that some GPs suggest it is useful to take Aspirin whilst on Tamoxifen to offset Tamoxifen's DVT side effects, just before and during long-haul flights, rail journeys or long periods of being sedentary.
Anyone seen any of this, or is on any trials for Aspirin?
Cheers
