5th Chemo

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My 5rd chemo visit on 25th September 2024:

First, more good news - PSA has now dropped from:

2.07 at referral for investigation of recurrence

1.22 (1/7/24)

0.54 (22/7/24)

0.19 (14/8/24)

0.08 (04/09/24). 

‹0.05 (25/09/24)

I feel very lucky and grateful to see these sustained improvements to lows I've never experienced before. It certainly makes the treatment effects worth tolerating and provides a huge boost in confidence.

No ECG required before treatment due to previous ones being good. Might need one next time if Consultant decides he wants to see one.

Cannula inserted at 2nd attempt again, first attempt by nurse unsuccessful (felt like a 6 inch nail was going in but I think I put on a brave face and didn't show myself up) - then yet another of the resident "experts" was  called and sucessfully inserted on first attempt. Infusion completed with no issues other than delays due to a very busy unit and my chemo preparation being delivered late. Not to worry, nothing much else to do on a dull, wet afternoon.

Same package of drugs to take home as before including mouthwashes to head off mouth problems if they start as on first three cycles. I have started using these straight away to try to head off problems earlier which worked last cycle, so hoping for a repeat this time around. Unfortunately a shortage of Darolutamide in the pharmacy resulted in only 4 days supply being availale so need to call back to chemo unit in 2 days to collect the remainder of my 3 week supply.

Felt fine morning after, we'll see how it goes in due course, hopefully no worse than cycle 4 which was the worst so far.

Anonymous
  • As the old British Rail slogan went "we're getting there" and you are!! A PSA of <0.05 makes my 0.29 after 30 months of HT positively massive. Open mouth!!  You are doing great and another slogan sums it up - no pain - no gain!!

    Cracking results and it's great you are feeling positive about the treatment - here's to minimum side effects from Cycle 5.

    Best wishes - Brian.

  • Hi Excavator,

    thank you so much for the detailed experience with this treatment and I’m so pleased it’s working out well for despite the side effects.

    for my part I’m just a week post second treatment and keeping a diary which I believe will be of benefit as time goes on. I’m using your advice on my side effects as they have been similar so far.

    one thing that seems to differ from my experience is they won’t give me the PSA numbers, as they may cause unnecessary concern if the changes aren’t as expected. Having pressed the nurse she did say there has been a reduction.

    I appreciate we are all different but preparing myself for the latter stages.

     Wish you the very best for the remaining session, you sound like the sort of person who will see it through.

    All the very best.

    Chris.

  • Great to hear your numbers. Canula insertion does seem to be an acquired skill, there seem to be 'go to' people in every chemo ward!  My veins look like a motorway map and I am very popular for canula insertion, with cries of 'I'll do him' with the nurses positively jostling to stab me! Only had one botched attempt so far. Good luck with the next cycle.

  • Thank you Chris.

    I find keeping a diary is a good way to monitor side effects etc. as you progress through treatment and enables me to get a better idea on how these difffer with each cycle. I had chemo for an unrelated cancer 10 years ago and did this at the time, so learnt a lot from that.

    Fortunately I have not had any problem obtaining blood test results from each cycle and in my case this has given great encouragement seeing my PSA reduce. From what I've seen others say, it is not uncommon for some to experience very slowly falling or,in some cases, rising PSA when progressing through chemo cycles and it's apparently not unusual for this to occur - it must be very disconcerting though?

    I'm pleased that my blog is of some help, if there are any specifics you'd like to ask as you progress just let me know and I'll do what I can to answer. In the meantime I wish you all the best for the rest of yours.

    Derek.