New diagnosed

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Hi everyone,

I’m writing about my father’s recent diagnosis and would appreciate your insights.

He has been diagnosed with prostate adenocarcinoma, Gleason score 3+4 (Grade Group 2), but about 50% of the cancer shows a cribriform pattern. Perineural invasion (PNI) is also present. His PSA is around 5 ng/mL.

A recent CT scan showed two sclerotic lesions:

  • One measuring 12 x 3 x 13 mm in the iliac bone

    Another 5 mm lesion in the thoracic spine (Th6)

  • Hi Littlebird17,

    I can see that no one has replied to you following your original post, so this reply will bump it back to the top of the pile again.  I'm sure someone will be along shortly with some input for you (it does tend to be a little wuieter on here at the weekend).

    One thing that may be of use is to know how old your father is.

    Best Wishes

    Brian

  • Hi Brian, thank you Blush My father is 69 years old. I'm sure someone reply soon.

  • Littlebird17 is right to say someone will be along soon with some generic advice for your father’s condition but I bet you really want to ask specific questions.

    It’s only natural to be so very out of your depth in the early days of diagnosis and the start of treatments especially if you’re not in the passenger seat at meetings. But even if you are there listening to clinicians be brave enough to ask for explanations and if you can scratch down what’s said.

    You are in the right place, be brave and ask what you like.

  • Hello  

    Welcome to the group although I am so sorry to find you here - I had a family day yesterday so that's my excuse for not replying!!

    So a few explanations:

    * Prostate Adenocarcinoma - This is the most common type of prostate cancer.

    * Gleason 7 (3+4) is a low 7 (Grade Group 2) - so most of the cancer cells found in the biopsy look likely to grow slowly whilst some will grow at a moderate rate.

    * Cribriform Pattern - is a different growth which would indicate an aggressive cancer and usually graded Gleason 8!!

    (statements 2 and 3 are conflicting I know! Perhaps the cribriform pattern was less than 50%!).

    * Perineural Invasion - this is where the cancer has grown around the nerves inside the Prostate.

    * Sclerotic lesions - these are symptoms of bone hardening and can be caused by cancer but also can be caused for other reasons as you get older.

    I would have thought in view of the last comment your dad would have had a bone scan before any treatment plan was offered

    I hope the above helps - if you have any specific questions or you need any further information please do get back to me.

    Best wishes - Brian.

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