Hi. I was diagnosed with stage 4 peritoneal cancer in February 2021 (stage 4 because had pleural effusion). I started chemotherapy in March (Paclitaxel and Carboplatin), had 3 cycles and then debulking surgery (hysterectomy , removal of omentum and a bowel resection). It was pretty scary to contemplate but surgeon was amazing, visited me every day after the op and was very positive. Then had 3 more cycles of chemo plus Avastin. Unfortunately CA125 started creeping up again and Avastin was halted. CT scan didn’t show disease spreading but oncologist recommended further chemotherapy, this time with Carboplatin and Caelyx. I decided to go ahead as like to feel I’m being proactive. Had a bit of blip when CA125 continued rising and I had to be admitted to hospital to have pleural effusion drained (3 litres!!) but oncologist was encouraging about continuing treatment as she said Caelyx sometimes took time to kick in and she was right. After six cycles of that have now been put on Rucaparib as maintenance therapy. Am only in first month of taking it so don’t know if it will be effective but am feeling really tired and breathless - wondered if anyone else has experience of this treatment?
Thank you for the reassurance, I’m having my first blood’s tomorrow so should know how the Rucaparib is affecting me, it’s been mostly fatigue and some shortness of breath but it’s early days so I’m trying to stay hopeful, good luck with your onward journey
Hi
thank you for your reply, not been on for a while , I’m 7 weeks on this medication now, and I fully understand the fatigue it has hit me really hard, just had all bloods checked and have been found to have anaemia so much so I’m having blood transfusion tomorrow, hoping that this will sort me out.
Nice to know that you have been on it for 4 years shows it can work and 3 monthly checks must be great , at first it just feels like hospital bloods & appointments at least with a break between you can get your life together, hope it continues to go well for you xx
Hi love hols,
I really hope the transfusion helps, it should do! I did have to drop in dose due to liver levels at the beginning. Once you feel up to it, perhaps you could try a little exercise VERY slowly. I joined a local chair fit class, was youngest by about 20 years but it's really helped!! I've had to reduce my working hours a bit but am finding a balance now. My CA125 levels have started creeping up though so waiting for a scan. Apparently they are also affected by any infection and stress so really hoping that's all it is! It's funny with the appointments, you want them looking after you but after a while it's nice to have a break between to fet on with life!! Good luck xx
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