I have stage IV lung cancer (bone mets, lymph nodes and brain mets which have been treated with gamma knife surgery in February). I started the above treatment in March and have had 4 cycles. My lung and spine tumours have shrank and there is reduced activity in my lymph nodes. Moving forward the Carboplatin will be dropped, so it will just be pemetrexed and pembrolizumab. Anyone who's had this treatment regime...when the Carboplatin was dropped did you still see a positive response to treatment? I'm worried that either the tumours will grow again or more metastases appear. Also did your treatment side effects change once the Carboplatin was dropped? I've had low neutrophils, feel nauseous/lose my appetite and feel exhausted for a few days after and I'm also anaemic. My consultant has implied that there may be a reduction in side effects...
Hello Jules1810,
I'm sorry you haven't received any replies to your questions yet.
I don't have any personal experience of your treatment as I just had a straight forward Cisplatin and Vinorelbine combination over 4 cycles.
However, I would think that by dropping Carboplatin your side effects should reduce and by maintaining Pemetrexed and Pembrolizumab there will continue to be a positive response to treatment as your consultant says.
I hope someone on here can give you a better response based on their own experience and my reply will put your post back at the top.
You could also try posting your questions on the chemotherapy forum which might elicit a reply. The link to this is Chemotherapy forum
I wish you all the best as you continue treatment.
Derek.
Macmillan Support Line - 0808 808 00 00, 7 days a week between 8am-8pm
Hi Dunno44
Oh poor you, I hope your body copes better when you have your next treatment.
I had my first cycle without the Carboplatin 3.5 weeks ago..my side effects were much reduced, no nausea or loss of appetite and not as tired. However at my pre-treatment check on Monday my bloods s
wed my Neutrophil count was too low to have treatment this week so they are postponing to next week they are ok otherwise I'll have to do the gcsf injections again.
TC and good luck
