My husband has been on 5mg Axitinib 2 daily with fortnightly Avelumab infusions since April 2021. Things were going great until around Christmas time when the side effects of the treatment started to get a bit overwhelming, particularly the diarrhoea which was pretty much every time he ate.. This culminated in an ambulance being called and a 2 day stay in hospital whilst they tried to sort him out, at the end of March.
once off the Axitinib the side effects cleared up pretty much instantly, the soreness gone within a couple of days and tummy back to normal within a week. It was lovely to see him back to his normal self and easy to forget that he actually has a kidney tumour 
since then, he has been put on a reduced dose of the Axitinib for the last four weeks which seems to be suiting him much better, although he say that he thinks he can feel his sore mouth and nose gradually coming back.
He has had great results on this treatment so far but I am concerned that being on the lower dose, although less severe in terms of the side effects, is not acting so well on reducing the tumour. He has a face to face appointment with the consultant on June 8th ( first face to face since his diagnosis) and I’m so worried there’s going to be bad news.
Hate this dark cloud that is constantly hanging over us.
Has anyone else reduced their Axitinib strength and how did you get on?
xx
Thank you. This is good to hear. He has a scan booked for July so 
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Hi there. Thanks for your message 
. He is continuing on the 3mg and has a scan booked for July. He consultant doesn’t seem too concerned and is actually very pleased with the progress so far. Feeling more positive. Xx
