PPI's?

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Hi all , been a while ,but i need ro know if anyone has any thoughts on PPI's ,ive been having nausea ( not being sick) for a few weeks ,Dr is thinking i have reflux so has prescribed lansoprazole. I just have an uneasy feeling in my stomach and gas ,no heartburn or indigestion. Not sure if its from when i had feeding tube in or due to me swallowing air ,has anyone had /has , this or on a ppi ? 

Thanks Mark 

  • I was given Omeprazole which didn't agree with me...I just toughed it out until it settled...seemed to be a PEG feeding issue...

    Michael

  • Hi Micheal ,sorry forgot to say this is 23 months post treatment ,tube was taken out 16 months back .

  • What I was told was that RT damage to the major salivary glands alters the balance between swallowed saliva which is alkaline  and gastric secretion which is acid. This can lead to reflux. My trust routinely prescribed PPI and it was suggested I might have to take Lansoprazole for life. I have since consulted with a gastroenterologist and he concurs. I’m happy with the drug so still take it. 

    Dani 

    Base of tongue cancer. T2N0M0 6 weeks Radiotherapy finished January 2019

    Macmillan Support Line -  0808 808 00 00 7 days a week between 8am-8pm

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  • Hi Dani,

    That makes a lot of sense really as i do swallow a lot of what saliva i do have trying to keep mouth moist ,if you can understand that ! I will give them a go see if it settles down .

    My consultant said we have no influence on producing saliva it comes when needed?  Hope your well good to here from you 

    Mark 

  • My consultant said we have no influence on producing saliva it comes when needed?  Hope your well good to here from you 

    That has to come with a caveat. You have two different types of saliva ( a simplification I must admit but I don’t want to tire you out with minutae.) 

    The submandibular glands produce background saliva to keep your mouth moist  The submandibulars are trashed by RT so you have a dry mouth. The oncologists try to spare one parotid and they react to food in your mouth,that’s why chewing gum works. 

    Dani 

    Base of tongue cancer. T2N0M0 6 weeks Radiotherapy finished January 2019

    Macmillan Support Line -  0808 808 00 00 7 days a week between 8am-8pm

    Community Champion badge

  • Thanks Dani ,it makes alot of sense ,i do love your knowledge! X