Paclitaxel v Abraxane

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Hello All,

I have Triple+ breast cancer grade 3 early stage (no lymph node involvement).

I am currently trying to complete neo-adjuvant chemo but proving allergic to every drug & battling every side-effect on the tin (neutropenia/ severe gut pain/ diarrhoea/ mucusitis/ tinnitus - the list goes on).

My chemo number is 5 per cent in terms of added life expectancy.

The plan is to switch me from Paclitaxel to Abraxane for 6 more weekly infusions. But it’s still a taxane and I know I will still get the side-effects. My team has already taken Docytaxel & Carboplatin off the table. 

Has anyone else with a similar allergic profile switched to Abraxane & had better/ similar experiences?

5 per cent currently feels like a small number!

Thanks so much for reading this.

  • Hi  

    I have had both Paclitaxel and Abraxane (NAB-Paclitaxel). Abraxane has the same active ingredient but a different suspension and I understand is much less likely to cause an allergic reaction. I hadn’t had a problem with Paclitaxel but was needing the drug a second time round. I found Abraxane a lot easier. No need for the steroids and anti histamines. Quite a smooth treatment. 

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