Abemaciclib 2 year tablet

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Hi

Abemaciclib - i started on this Mid April 2026 and dose reduced to 100mg 5 weeks ago.

Diarrhoea is the main issue, 2-3 times per day. Told to take Imodium {Lopermide} 2.5mg at first loose motion.

my concern is taking Loperamide over 2 years what impact will it have on the bowels.

or is this something we just have to go with.

I had lumpectomy, Grade 3, hormone fed cancer and 4 cancerous lymphnodes, chemo, radiotherapy and Letrozole.

any thoughts

thank you