Hi, I have been on abemaciclib for 18 months, along with tamoxifen, and the laste 3-ish months I have been extremely tired, much more so than usual. I also have achey thigh muscles when I go up stairs or stand from a chair. Not the most horrendous side effects I know but the tiredness is really getting to me. I don't want to lower my dose so I will persevere with it, until the end of the 2 years.
Has anyone got any experience of how quickly you feel better (if at all?) once you come of abemacicilb?
Thanks
Hi, I finished my 2 years on abemaciclib on May 3rd this year. I definitely feel better now and hope to improve some more. I’d say the first 2-3 weeks the improvement in how I felt was due to the psychological boost I experienced, but I am now definitely less tired and the mild depression has lifted.
I went through on the 150mg dose, though I felt very ground down last winter and this spring. I asked about lowering the dose, but was advised that my blood test results did not really warrant it, best to stick with 150mg. So I did, but I had a few infections and not a lot of energy. A low point was developing a “running sore” on my leg in March.
Letrozole hadn’t bothered me much at all in the 4.5 months I had it for before adding abemaciclib, so I’m hoping for improved balance, slightly thicker hair and less flaky finger and toe nails and skin less dry.
I had trouble with watering eyes and blocked sinuses , but that has now worn off.
Anyway I’m so glad to have finished the pills!
All the best to you!!!
Thank you, that sounds positive. It does just grind you down, I was ill the whole of April and May with one thing after another, throat infection, chest infection, sinus infection. Bloody wearing!
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