Palbociclib and Letrozole

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My wife who is 77 has been receiving both drugs for 5.5 years and they have certainly stopped her cancer coming back. 
However over the last 6-9 months she has developed ‘brain fog ‘ type symptoms and short term memory impairment. It is not normal aging and I read that long term exposure to Letrozole can impair cognitive function. I wonder whether this is something others have experienced and what if any steps have been taken to help. Lynda is waiting for an appointment at a local Memory Service Clinic….

Thank you.