Side effects

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Hi. I take abemaciclib,exemestane and zoladex . I was doing okay then had to take a break for antibiotics due to a cough. Started again ( also changed fom tamoxifen to exemestane and the sane time)  the side effects are now flooring me ! No energy.  Sore joints.  Awful pressure headaches and sore on right side on my head and neck. Ive been advised to take a 2 week break. Anyone else having issues? I really want to get fit again  ! Im exhausted all the time