Abemaciclib long term data in Early Breast cancer

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Hi to all the Abemaciclib users for early breast cancer  Wave - hope everyone is doing well! 

There was some new data announced at the annual scientific medical oncology congress (ESMO) over the weekend and I thought it would be interesting to share in case you haven’t seen it - here’s a link:

https://dailyreporter.esmo.org/esmo-congress-2023/breast-cancer/sustained-efficacy-of-cdk-inhibitors-reported-for-hr-her2-high-risk-early-breast-cancer

One of the key highlights for me was about dose reductions as I’m on 100mg dose and have worried whether it’s as effective as the higher dose: 

“the effect of abemaciclib appeared similar when administered at a twice-daily dose of 150 mg versus either 100 mg or 50 mg…it is very important in the curative setting for the agent to be well-tolerated so that patients can continue to receive treatment for an extended period whilst maintaining a good quality of life.” 

I hope this information is useful - it might be worthwhile showing this to your oncologist and get her / him to share their views with you about the data and what it might mean for you.  It has definitely made me feel more positive about taking the drug for the 2 year period. :) 

Take care xxx