Abemaciclib zoledronic acid

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Hi all

I had my first zoledronic acid infusion on Thursday and started Abemaciclib on Friday.  Only been on 2 days and the nausea is killing me.  Has anyone else had this? Is it the fusion or Abemaciclib.  I can’t believe I feel so sick.  The anti sickness tablets are not really working.  Can anyone help, please x 

  • Hi, sorry to hear you are feeling so unwell. 

    I had nausea when I started taking abemaciclib, last a couple of weeks, also had with 1st Zoldronic acid infusion for a few days. 

    Sounds like you are having a double whammy as stated both about same tune. 

    I found it passes but very unpleasant!

    Best wishes, hopefully you will feel better very soon x

  • Hi Kitty 

    Thanks for response. Been taking on an empty stomach.  As I’ve been feeling so sick been taking on a empty stomach so gonna try with food.  Did you have sickness with acid and Abemaciclib.  I’ve lost my taste as well, did you suffer with this? 

  • Yes sickness with both. Few days after the infusion, but a couple of weeks with abemaciclib 

    I lost taste too with abemaciclib, but did improve after a couple of months

    Try just eating things like, white bread, white rice, just bland carbs for a few days. Get plenty of fluids, water or weak squash. 

    Abemaciclib can be tough at first, I had bad stomach cramps & diarrhoea

    Take care x